Geert Jan Groeneveld Selected Research

PF-06372865

8/2019

Analgesic potential of PF-06372865, an α2/α3/α5 subtype-selective GABAA partial agonist, in humans.

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Geert Jan Groeneveld Research Topics

Disease

16	Pain (Aches) 11/2022 - 09/2013
8	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2017
8	Cognitive Dysfunction 11/2021 - 10/2016
4	Respiratory Insufficiency (Respiratory Failure) 01/2022 - 09/2013
4	Neuralgia (Stump Neuralgia) 08/2019 - 01/2016
3	Apnea 01/2022 - 01/2017
3	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2022
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 11/2017
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2020 - 08/2009
2	Multiple Sclerosis 01/2022 - 01/2020
2	Inflammation (Inflammations) 01/2022 - 01/2020
2	Dementia (Dementias) 01/2022 - 09/2021
2	Hyperhidrosis 01/2021 - 04/2010
2	Peripheral Nervous System Diseases (PNS Diseases) 01/2020 - 01/2018
2	Polyneuropathies (Polyneuropathy) 01/2020 - 04/2017
2	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2019 - 08/2009
2	Disease Progression 12/2018 - 08/2009
1	Opioid-Related Disorders (Opiate Addiction) 01/2022
1	Neuroinflammatory Diseases 01/2021
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2020
1	Diabetic Neuropathies (Diabetic Neuropathy) 01/2020
1	Tremor (Tremors) 01/2020
1	Lennox Gastaut Syndrome 01/2020
1	Muscular Atrophy (Muscle Atrophy) 01/2019
1	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2019
1	Long Term Adverse Effects 01/2019
1	Chronic Pain 01/2018
1	Multiple Myeloma 01/2018
1	Painful Neuropathy 01/2018
1	Type 2 Diabetes Mellitus (MODY) 04/2017
1	Miosis 01/2017
1	Hyperalgesia 10/2016
1	Burns 10/2016
1	Sciatica (Sciatic Neuralgia) 01/2016

Drug/Important Bio-Agent (IBA)

8	Analgesics (Analgesic Drugs)IBA 01/2021 - 01/2016
7	Cholinergic Agents (Cholinergics)IBA 01/2022 - 10/2016
7	Pharmaceutical PreparationsIBA 01/2020 - 04/2010
4	Galantamine (Galanthamine)FDA LinkGeneric 01/2022 - 01/2018
4	Fentanyl (Sublimaze)FDA LinkGeneric 01/2022 - 09/2013
4	Opioid Analgesics (Opioids)IBA 01/2022 - 10/2016
4	Pregabalin (Lyrica)FDA Link 01/2020 - 01/2017
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2018
3	Ibuprofen (Motrin)FDA LinkGeneric 01/2020 - 01/2017
3	MecamylamineIBA 11/2019 - 01/2018
2	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2022 - 01/2019
2	LigandsIBA 01/2022 - 01/2016
2	Apomorphine FDA Link 01/2022 - 01/2022
2	Muscarinic M1 ReceptorIBA 11/2021 - 09/2021
2	Capsaicin (Zostrix)FDA Link 01/2021 - 10/2016
2	Huntingtin ProteinIBA 01/2021 - 01/2020
2	Bortezomib (Velcade)FDA Link 01/2020 - 01/2018
2	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 11/2019 - 11/2018
2	Nicotine FDA Link 11/2018 - 01/2018
1	Voltage-Gated Sodium Channel BlockersIBA 11/2022
1	Buprenorphine (Subutex)FDA LinkGeneric 01/2022
1	SynucleinsIBA 01/2022
1	mu Opioid Receptors (mu Opioid Receptor)IBA 01/2022
1	Voltage-Gated Sodium ChannelsIBA 01/2022
1	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 11/2021
1	Amyloid (Amyloid Fibrils)IBA 01/2021
1	Apolipoproteins E (ApoE)IBA 01/2021
1	CannabidiolIBA 01/2020
1	Methylphenidate (Ritalin)FDA LinkGeneric 01/2020
1	Clobazam (HR 376)IBA 01/2020
1	NexusIBA 01/2020
1	Sodium Channels (Sodium Channel)IBA 01/2020
1	CytokinesIBA 01/2020
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2020
1	Sodium Channel BlockersIBA 01/2020
1	PF-05089771IBA 01/2020
1	PF-06372865IBA 08/2019
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2019
1	Messenger RNA (mRNA)IBA 01/2019
1	RG7800IBA 01/2019
1	Proteins (Proteins, Gene)FDA Link 01/2019
1	Donepezil (Aricept)FDA LinkGeneric 01/2019
1	ezogabine (retigabine)IBA 12/2018
1	Riluzole FDA LinkGeneric 12/2018
1	PF-06273340IBA 01/2018
1	Nerve Growth Factor (NGF)IBA 01/2018
1	coenzyme Q10 (CoQ10)IBA 11/2017
1	Simvastatin (Zocor)FDA LinkGeneric 11/2017
1	ubiquinolIBA 11/2017
1	NAD (NADH)IBA 04/2017
1	Opioid Receptors (Opioid Receptor)IBA 01/2017
1	Xen2174IBA 01/2017
1	6'- fluoro- 4',9'- dihydro- N,N- dimethyl- 4- phenylspiro(cyclohexane- 1,1'(3'H)- pyrano(3,4- b)indol)- 4- amineIBA 01/2017
1	Phenytoin (Dilantin)FDA LinkGeneric 01/2017
1	EsketamineIBA 01/2017
1	NociceptinIBA 01/2017
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 10/2016
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 10/2016
1	N-Methylaspartate (NMDA)IBA 10/2016
1	Scopolamine (Hyoscine)FDA Link 10/2016

Therapy/Procedure

4	Analgesia 01/2021 - 09/2013
2	Therapeutics 01/2022 - 01/2018
1	Injections 01/2022
1	Subcutaneous Injections 01/2022
1	Surgical Instruments (Clip) 01/2020
1	Intravenous Injections 01/2016